PTSDgene database

SNP Report

Basic Info
Name rs6703669 dbSNP Ensembl
Location 1:46396883 - 46396883(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.13119
Annotation intron_variant; non_coding_transcript_variant
Variant Effect intron_variant(ENST00000493735, ENST00000468718, ENST00000243167); non_coding_transcript_variant(ENST00000493735, ENST00000468718)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000243167)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000243167)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers;Active TSS;Bivalent Enhancer
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Pardini, M.,2012 PTSD C/- compared with T/T: In TPBI subjects without vmPFC lesi...... C/- compared with T/T: In TPBI subjects without vmPFC lesions: P-value= 0.18. In the vmPFC lesion group: P-value= 0.34. More... No significant difference in PTSD prevalence between genotyp...... No significant difference in PTSD prevalence between genotypes in both subjects. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
FAAH fatty acid amide hydrolase 1p35-p34 8(3/5/0)

SNPs in LD with rs6703669 (count: 170)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 170)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx