SNP Report

Basic Info

Name	rs7126715 dbSNP Ensembl
Location	11:63414285 - 63414285(+)
Variant Seq	A
Ancestral Allele	A
Ref Seq	G
Minor Allele Frequence	0.466254
Annotation	downstream_gene_variant
Variant Effect	downstream_gene_variant(ENST00000536333, ENST00000279178)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000279178)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000279178)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Solovieff, N.,2014	PTSD diagnosis	P-value=0.210 P-value=0.210	Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
DRD4	dopamine receptor D4	11p15.5	7(2/5/0)
SLC22A9	solute carrier family 22 (organic anion transporter), member 9	11q12.3	Mapped by Literature SNP, Mapped by LD-proxy

SNPs in LD with rs7126715 (count: 88)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 88)

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs4313592	rs7126715	downstream_gene_variant	1.0000[EUR]
rs681291	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8322[EUR]
rs631157	rs7126715	intron_variant; NMD_transcript_variant	0.8270[EUR]
rs4963267	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9211[EUR]
rs642637	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9464[EUR]
rs4088473	rs7126715	downstream_gene_variant	0.8388[EUR]
rs537473	rs7126715	intron_variant; NMD_transcript_variant	0.8270[EUR]
rs4246213	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7927856	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8442[EUR]
rs866905	rs7126715	downstream_gene_variant	0.9598[EUR]
rs4466837	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8071[EUR]
rs627647	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8203[EUR]
rs2212017	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9399[EUR]
rs4088470	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4963416	rs7126715	intron_variant; NMD_transcript_variant	0.8441[EUR]
rs11231494	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8071[EUR]
rs6591801	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9277[EUR]
rs4102215	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8203[EUR]
rs4370940	rs7126715	intron_variant; NMD_transcript_variant	0.8441[EUR]
rs9666270	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7109920	rs7126715	intron_variant; NMD_transcript_variant	0.8270[EUR]
rs4963412	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4088469	rs7126715	intron_variant; NMD_transcript_variant	0.9865[EUR]
rs2000491	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9005[EUR]
rs4357693	rs7126715	intron_variant; NMD_transcript_variant	0.9865[EUR]
rs7104097	rs7126715	downstream_gene_variant	1.0000[EUR]
rs668284	rs7126715	downstream_gene_variant	0.8388[EUR]
rs630759	rs7126715	intron_variant; NMD_transcript_variant	0.8270[EUR]
rs7127167	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8071[EUR]
rs631174	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9344[EUR]
rs7116119	rs7126715	intron_variant; NMD_transcript_variant	0.9465[EUR]
rs613729	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8203[EUR]
rs28828158	rs7126715	downstream_gene_variant	0.8020[EUR]
rs560011	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9798[EUR]
rs4506657	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9005[EUR]
rs10897414	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9211[EUR]
rs665080	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8322[EUR]
rs4246214	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4102216	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9464[EUR]
rs11231478	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9277[EUR]
rs523493	rs7126715	downstream_gene_variant; 3_prime_UTR_variant	0.8441[EUR]
rs4582980	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9138[EUR]
rs537178	rs7126715	downstream_gene_variant	0.8388[EUR]
rs10897415	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9412[EUR]
rs4963415	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4088472	rs7126715	downstream_gene_variant	1.0000[EUR]
rs9665791	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4963265	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9335[EUR]
rs637122	rs7126715	downstream_gene_variant	0.8218[EUR]
rs7935983	rs7126715	downstream_gene_variant	1.0000[EUR]
rs501657	rs7126715	downstream_gene_variant	0.8441[EUR]
rs7118732	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7112909	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7109027	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7129183	rs7126715	intron_variant; NMD_transcript_variant	0.9865[EUR]
rs524339	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8203[EUR]
rs629479	rs7126715	intron_variant; NMD_transcript_variant	0.8375[EUR]
rs4454724	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9005[EUR]
rs515867	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8020[EUR]
rs9665872	rs7126715	intron_variant; NMD_transcript_variant	1.0000[EUR]
rs12792143	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9136[EUR]
rs642659	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9464[EUR]
rs7116851	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9344[EUR]
rs58520445	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9398[EUR]
rs4369413	rs7126715	downstream_gene_variant	1.0000[EUR]
rs60092232	rs7126715	synonymous_variant; 5_prime_UTR_variant; upstream_gene_variant; 3_prime_UTR_variant; stop_gained; intron_variant; NMD_transcript_variant	0.8020[EUR]
rs11534561	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8749[EUR]
rs11534566	rs7126715	downstream_gene_variant; splice_donor_variant; upstream_gene_variant; intron_variant; NMD_transcript_variant	0.8020[EUR]
rs7131511	rs7126715	downstream_gene_variant	1.0000[EUR]
rs7111246	rs7126715	downstream_gene_variant	1.0000[EUR]
rs866906	rs7126715	downstream_gene_variant	0.9466[EUR]
rs537227	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8255[EUR]
rs4963411	rs7126715	downstream_gene_variant	1.0000[EUR]
rs2226452	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8020[EUR]
rs7937224	rs7126715	downstream_gene_variant	0.9530[EUR]
rs36127182	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9344[EUR]
rs4369412	rs7126715	downstream_gene_variant	1.0000[EUR]
rs518291	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9412[EUR]
rs4088474	rs7126715	downstream_gene_variant	1.0000[EUR]
rs4963413	rs7126715	downstream_gene_variant	1.0000[EUR]
rs593748	rs7126715	downstream_gene_variant	0.8388[EUR]
rs536994	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8270[EUR]
rs7121823	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9865[EUR]
rs7111451	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.9016[EUR]
rs6591805	rs7126715	synonymous_variant; intron_variant; NMD_transcript_variant	0.8071[EUR]
rs6591796	rs7126715	downstream_gene_variant	1.0000[EUR]
rs629907	rs7126715	intron_variant; NMD_transcript_variant	0.8270[EUR]
rs7937356	rs7126715	intron_variant; NMD_transcript_variant	1.0000[EUR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx