PTSDgene database

SNP Report

Basic Info
Name rs7126715 dbSNP Ensembl
Location 11:63414285 - 63414285(+)
Variant Seq A
Ancestral Allele A
Ref Seq G
Minor Allele Frequence 0.466254
Annotation downstream_gene_variant
Variant Effect downstream_gene_variant(ENST00000536333, ENST00000279178)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000279178)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000279178)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD diagnosis P-value=0.210 P-value=0.210 Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... Non-significant

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DRD4 dopamine receptor D4 11p15.5 7(2/5/0)
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 11q12.3 Mapped by Literature SNP, Mapped by LD-proxy

SNPs in LD with rs7126715 (count: 88)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 88)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx