PTSDgene database

SNP Report

Basic Info
Name rs752306 dbSNP Ensembl
Location 11:637622 - 637622(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.0794728
Annotation upstream_gene_variant; intron_variant
Variant Effect upstream_gene_variant(ENST00000528733); intron_variant(ENST00000176183)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000176183)
PolyPhen Annotation unknown
PolyPhen Variant Effect unknown(ENST00000176183)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Bivalent/Poised TSS;Flanking Bivalent TSS/Enh;Bivalent Enhancer;Active TSS;Weak transcription;Enhancers;Transcr. at gene 5' nd 3'
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD severity P-value=0.292 P-value=0.292 Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DRD4 dopamine receptor D4 11p15.5 7(2/5/0)

SNPs in LD with rs752306 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx