SNP Report
Basic Info
| Name | rs752306 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:637622 - 637622(+) | ||
| Variant Seq | T | ||
| Ancestral Allele | C | ||
| Ref Seq | C | ||
| Minor Allele Frequence | 0.0794728 | ||
| Annotation | upstream_gene_variant; intron_variant | ||
| Variant Effect | upstream_gene_variant(ENST00000528733); intron_variant(ENST00000176183) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000176183) | ||
| PolyPhen Annotation | unknown | ||
| PolyPhen Variant Effect | unknown(ENST00000176183) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | TF binding region | ||
| Chromatin State | Bivalent/Poised TSS;Flanking Bivalent TSS/Enh;Bivalent Enhancer;Active TSS;Weak transcription;Enhancers;Transcr. at gene 5' nd 3' | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD severity | P-value=0.292 P-value=0.292 | Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| DRD4 | dopamine receptor D4 | 11p15.5 | 7(2/5/0) |
SNPs in LD with rs752306 (count: 0)
SNP related eQTL (count: 1)