PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

Study Report

Study Information

Basic Info

Reference	Dragan, W. L.,2009 PMID: 19330578
Citation	Dragan, W. L. and W. Oniszczenko (2009). "The association between dopamine D4 receptor exon III polymorphism and intensity of PTSD symptoms among flood survivors." Anxiety Stress Coping 22(5): 483-495.
Phenotype	Intrusion/Arousal symptoms, Avoidance/Numbing symptoms, PTSD-C score, PTSD-F score
Trauma	Flood
Study Design	Cross-sectional study
Study Type	Candidate gene association study
Sample Size	107 samples
SNP/Marker Size	1 Variant
Predominant Ethnicity	Caucasian
Population	Poland
Gender	57 females, 50 males
Age	Mean age=35.57 years, SD=12.89

Detail Info

Genetic result reported by this study

Normal genetic result reported by this study (count: 4)

Marker	Phenotype	Related Gene	Statistical Values	Author Comments	Marker's Category
DRD4_exon3_VNTR	PTSD-C score	DRD4	F=4.01, P-value=0.048	A main effect of genotype was found for Total PTSD-F. A main effect of genotype was found for Total PTSD-F.	Significant
DRD4_exon3_VNTR	PTSD-F score	DRD4	F=3.23, P-value=0.075	A trend was also found for the PTSD-C score. A trend was also found for the PTSD-C score.	Non-significant
DRD4_exon3_VNTR	Avoidance/Numbing symptoms	DRD4	F=4.57, P-value=0.035	A main effect of genotype was found for AN. A main effect of genotype was found for AN.	Significant
DRD4_exon3_VNTR	Intrusion/Arousal symptoms	DRD4	F=1.89, P-value=0.17	No significant differences between groups differing in genot...... No significant differences between groups differing in genotype were found for I/A PTSD-F scores. More...	Non-significant