PTSDgene database

SNP Report

Basic Info
Name rs6869645 dbSNP Ensembl
Location 5:1404433 - 1404433(+)
Variant Seq T
Ancestral Allele T
Ref Seq C
Minor Allele Frequence 0.0764776
Annotation upstream_gene_variant; intron_variant
Variant Effect upstream_gene_variant(ENST00000512002); intron_variant(ENST00000270349)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000270349)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000270349)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Nelson, E. C.,2014 PTSD P-value=0.0076, OR=1.22 P-value=0.0076, OR=1.22 Although the association of this SNP is of considerably lowe...... Although the association of this SNP is of considerably lower magnitude, it is interesting to note. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 21(11/10/0)

SNPs in LD with rs6869645 (count: 12)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 12)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1-IT1 Yes Adipose Subcutaneous cis GTEx