PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

Study Report

Study Information

Basic Info

Reference	Duan, Z. X.,2014 PMID: 24817970
Citation	Duan, Z. X., et al. (2014). "Clinical relevance of tag single nucleotide polymorphisms within the CAT gene in patients with PTSD in the Chongqing Han population." Int J Clin Exp Pathol 7(4): 1724-1732.
Phenotype	PTSD diagnosis
Trauma	Various
Study Design	Case-control
Study Type	Candidate gene association study
Sample Size	173 cases, 287 controls
SNP/Marker Size	6 SNPs
Predominant Ethnicity	Mongloid
Population	Chinese Han
Gender	Case: 70 females, 103 males. Control: 112 females, 175 males
Age	Case: mean age=36 years, SD=6.90. Control: mean age=35 years

Detail Info

Genetic result reported by this study

Normal genetic result reported by this study (count: 11)

Marker	Phenotype	Related Gene	Statistical Values	Author Comments	Marker's Category
rs10836233	PTSD diagnosis	CAT	Codominant effect: P-value=0.35; Dominant effect: P-value=0.18; Recessive effect: P-value=1.00	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant
rs769217	PTSD diagnosis	CAT	Codominant effect: P-value=0.17; Dominant effect: P-value=0.25; Recessive effect: P-value=0.33	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant
rs7104301	PTSD diagnosis	CAT	Codominant effect: P-value=0.56; Dominant effect: P-value=0.33; Recessive effect: P-value=1.00	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant
rs208679 - rs10836233 - rs2300182 - rs769217 - rs7104301 - rs7949972, GGTTGT	PTSD diagnosis	CAT	X²=0.05, P-value= 0.81	No significant results. No significant results.	Non-significant
rs208679 - rs10836233 - rs2300182 - rs769217 - rs7104301 - rs7949972, AGTTAT	PTSD diagnosis	CAT	X²=13.45, P-value<0.001	Ht4 had a risk effect on PTSD development. Ht4 had a risk effect on PTSD development.	Significant
rs208679 - rs10836233 - rs2300182 - rs769217 - rs7104301 - rs7949972 ,AGTCAC	PTSD diagnosis	CAT	X²=2.54, P-value= 0.11	No significant results. No significant results.	Non-significant
rs208679 - rs10836233 - rs2300182 - rs769217 - rs7104301 - rs7949972, AATCAC	PTSD diagnosis	CAT	X²=6.55, P-value= 0.01	Ht2 had a risk effect on PTSD development. Ht2 had a risk effect on PTSD development.	Significant
rs7949972	PTSD diagnosis	CAT	Codominant effect: P-value=0.88; Dominant effect: P-value=0.69; Recessive effect: P-value=0.90	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant
rs208679	PTSD diagnosis	CAT	Codominant effect: P-value=0.38; Dominant effect: P-value=0.29; Recessive effect: P-value=0.26	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant
rs208679 - rs10836233 - rs2300182 - rs769217 - rs7104301 - rs7949972, AAACAC	PTSD diagnosis	CAT	X²=0.09, P-value= 0.77	No significant results. No significant results.	Non-significant
rs2300182	PTSD diagnosis	CAT	Codominant effect: P-value=0.49; Dominant effect: P-value=1.00; Recessive effect: P-value=0.35	We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More...	Non-significant