PTSDgene database

SNP Report

Basic Info
Name rs7949972 dbSNP Ensembl
Location 11:34480495 - 34480495(+)
Variant Seq T
Ancestral Allele C
Ref Seq C
Minor Allele Frequence 0.419329
Annotation downstream_gene_variant; intron_variant
Variant Effect downstream_gene_variant(ENST00000579311, ENST00000528709); intron_variant(ENST00000312319, ENST00000429939, ENST00000620316, ENST00000257832)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000620316, ENST00000312319, ENST00000429939, ENST00000257832)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000620316, ENST00000312319, ENST00000429939, ENST00000257832)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Bivalent Enhancer;Enhancers;Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Duan, Z. X.,2014 PTSD diagnosis Codominant effect: P-value=0.88; Dominant effect: P-value=...... Codominant effect: P-value=0.88; Dominant effect: P-value=0.69; Recessive effect: P-value=0.90 More... We found that none of six tag SNPs of the CAT gene were sign...... We found that none of six tag SNPs of the CAT gene were significantly associated with the risk of PTSD in all alternative analysis model. More... Non-significant

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CAT catalase 11p13 1(1/0/0)
ELF5 E74-like factor 5 (ets domain transcription factor) 11p13-p12 Mapped by Literature SNP, Mapped by LD-proxy

SNPs in LD with rs7949972 (count: 4)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx