Gene Report

Basic Info

Approved Symbol	SKA2
Previous Symbol	FAM33A
Symbol Alias	FLJ12758
Approved Name	spindle and kinetochore associated complex subunit 2
Previous Name	family with sequence similarity 33, member A
Location	17q23.2
Position	chr17:59109951-59155269, -1
External Links	HGNC: 28006 Entrez Gene: 348235 Ensembl: ENSG00000182628 UCSC: uc010dde.1
No. of Association Results	2 (Positive: 0; Negative: 2; trend: 0)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy, rSNP target

Gene related association results

Normal genetic study related association results (count: 2)

Reference	Phenotype	Marker	Gene's Category
Sadeh, N.,2016	PTSD diagnosis	rs7208505	Non-significant
Sadeh, N.,2016	PTSD symptoms	rs7208505	Non-significant

Gene functional annotation

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0007264	small GTPase mediated signal transduction	biological process	TAS	14
GO:0031110	regulation of microtubule polymerization or depolymerization	biological process	IDA[19289083]	1
GO:0008017	microtubule binding	molecular function	IDA[19289083]	6
GO:0000940	condensed chromosome outer kinetochore	cellular component	IDA[17093495\|19289083]	1
GO:0000278	mitotic cell cycle	biological process	TAS	7
GO:0051301	cell division	biological process	IMP[17093495]	5
GO:0007067	mitotic nuclear division	biological process	IMP[19289083]	6
GO:0007059	chromosome segregation	biological process	IMP[19289083]	3
GO:0005829	cytosol	cellular component	TAS	78
GO:0005515	protein binding	molecular function	IPI[17093495\|19289083\|19360002\|26496610]	169
GO:0005876	spindle microtubule	cellular component	IDA[17093495\|19289083]	3

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 1)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
SKA2	DSN1	No	--	--	22371557 , 22371557