SNP Report
Basic Info
| Name | rs11606304 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 11:18030701 - 18030701(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | T | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.0283546 | ||
| Annotation | intron_variant; NMD_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000417164, ENST00000528338, ENST00000250018); NMD_transcript_variant(ENST00000417164) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000250018) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000250018) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 2 (Positive: 0; Negative: 2; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD diagnosis | P-value=0.077 P-value=0.077 | Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... | Non-significant |
| Solovieff, N.,2014 | PTSD severity | P-value=0.120 P-value=0.120 | Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| TPH1 | tryptophan hydroxylase 1 | 11p15.3-p14 | 5(1/4/0) |
SNPs in LD with rs11606304 (count: 0)
SNP related eQTL (count: 1)