PTSDgene database

SNP Report

Basic Info
Name rs3213207 dbSNP Ensembl
Location 6:15627871 - 15627871(+)
Variant Seq C
Ancestral Allele T
Ref Seq T
Minor Allele Frequence 0.0591054
Annotation intron_variant; NMD_transcript_variant
Variant Effect intron_variant(ENST00000344537, LRG_588t2, ENST00000510395, ENST00000355917, ENST00000513680, ENST00000511762, LRG_588t1, ENST00000622898, ENST00000515875, ENST00000338950, ENST00000506844); NMD_transcript_variant(ENST00000510395, ENST00000513680, ENST00000515875, ENST00000506844)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000344537, LRG_588t1, ENST00000622898, ENST00000355917, ENST00000338950, LRG_588t2); tolerated(ENST00000515875, ENST00000511762)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000344537, ENST00000515875, LRG_588t1, ENST00000355917, ENST00000338950, ENST00000511762, LRG_588t2); possibly_damaging(ENST00000622898)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers;Flanking Active TSS
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD severity P-value=0.434 P-value=0.434 Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DTNBP1 dystrobrevin binding protein 1 6p22.3 5(2/3/0)

SNPs in LD with rs3213207 (count: 12)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 12)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1 Yes Adipose Subcutaneous cis GTEx