
Gene Report
Approved Symbol | GABBR2 |
---|---|
Previous Symbol | GPR51 |
Symbol Alias | "HG20|GABABR2|GPRC3B" |
Approved Name | gamma-aminobutyric acid (GABA) B receptor, 2 |
Previous Name | G protein-coupled receptor 51 |
Location | 9q22.1-q22.3 |
Position | chr9:98288082-98709197, -1 |
External Links |
HGNC: 4507 Entrez Gene: 9568 Ensembl: ENSG00000136928 UCSC: uc004ays.3 |
No. of Association Results | 1 (Positive: 0; Negative: 0; trend: 1) |
Annotation Type | Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy |
Reference | Phenotype | Marker | Gene's Category |
---|---|---|---|
Xie, P.,2013 | Lifetime PTSD | rs2779551 | Trend |
ID | Name | Type | Evidence[PMID] | No. of Genes in PTSDgene |
---|---|---|---|---|
GO:0004965 | G-protein coupled GABA receptor activity | molecular function | IDA[9872316] | 1 |
GO:0030054 | cell junction | cellular component | IEA | 24 |
GO:0007214 | gamma-aminobutyric acid signaling pathway | biological process | IDA[9872316] | 4 |
GO:0005886 | plasma membrane | cellular component | TAS | 99 |
GO:0007268 | synaptic transmission | biological process | TAS | 32 |
GO:0038039 | G-protein coupled receptor heterodimeric complex | cellular component | IPI[9872316] | 1 |
GO:0005887 | integral component of plasma membrane | cellular component | IDA[9872316] | 36 |
GO:0007194 | negative regulation of adenylate cyclase activity | biological process | TAS[10328880] | 5 |
GO:0005737 | cytoplasm | cellular component | IEA | 109 |
GO:0045211 | postsynaptic membrane | cellular component | IEA | 21 |
GO:0043005 | neuron projection | cellular component | IEA | 17 |
GO:0005515 | protein binding | molecular function | IPI[16724110|24658140] | 169 |
GO:0007186 | G-protein coupled receptor signaling pathway | biological process | TAS[9872316] | 14 |
ID | Name | No. of Genes in PTSDgene |
---|---|---|
hsa04080 | Neuroactive ligand-receptor interaction | 22 |
Gene | Interactor | Interactor in PTSDgene? | Experiment Method | Interaction Type | PMID |
---|---|---|---|---|---|
GABBR2 | CERS2 | No | -- | -- | 20195357 |
GABBR2 | NSF | No | -- | colocalization | 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 , 16724110 |
GABBR2 | ATF5 | No | -- | -- | 11087824 |
GABBR2 | GRASP | No | -- | -- | 11850456 |
GABBR2 | GLP1R | No | -- | -- | 23864651 , 23864651 |
GABBR2 | ATF4 | No | -- | -- | 11087824 , 11087824 |
GABBR2 | SH3GL3 | No | -- | -- | 16169070 , 16169070 , 16169070 , 16169070 , 16169070 |
GABBR2 | HTR1A | Yes | -- | -- | 11854302 |
GABBR2 | GABBR1 | No | -- | -- | 16724110 , 16724110 , 10075644 , 16724110 , 9872316 , 9872316 , 9872316 |
Copyright: Key Lab of Mental Health, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: April 1, 2018