PTSDgene database

SNP Report

Basic Info
Name rs9923585 dbSNP Ensembl
Location 16:15983503 - 15983503(+)
Variant Seq C
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.0131789
Annotation intron_variant
Variant Effect intron_variant(ENST00000399410, ENST00000399408)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000575938, ENST00000255759); tolerated(ENST00000573087, ENST00000572415, ENST00000573429, ENST00000575073, ENST00000573396, ENST00000573968)
PolyPhen Annotation benign; possibly_damaging
PolyPhen Variant Effect benign(ENST00000573087, ENST00000572415); possibly_damaging(ENST00000575938, ENST00000573429, ENST00000255759, ENST00000575073, ENST00000573396, ENST00000573968)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Genic enhancers;Enhancers;ZNF genes & repeats
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Xie, P.,2013 Lifetime PTSD Trauma Exposed African Americans: in GWAS,P-value=1.74E-05,i...... Trauma Exposed African Americans: in GWAS,P-value=1.74E-05,in replication,P-value=NT,in combined, P-value=NT. More... No significant signals were observed in the African American...... No significant signals were observed in the African American part of the sample. Genome-wide association study analyses restricted to trauma-exposed individuals yielded very similar results. More... Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ABCC1 ATP binding cassette subfamily C member 1 16p13.1 1(0/0/1)

SNPs in LD with rs9923585 (count: 8)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 8)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx