Gene Report

Basic Info

Approved Symbol	ABCC1
Previous Symbol	"MRP\|MRP1"
Symbol Alias	GS-X
Approved Name	ATP binding cassette subfamily C member 1
Previous Name	"multidrug resistance associated protein 1\|ATP-binding cassette, sub-family C (CFTR/MRP), member 1"
Location	16p13.1
Position	chr16:15949577-16143074, 1
External Links	HGNC: 51 Entrez Gene: 4363 Ensembl: ENSG00000103222 UCSC: uc010bvi.3
No. of Association Results	1 (Positive: 0; Negative: 0; trend: 1)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy

Gene related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Marker	Gene's Category
Xie, P.,2013	Lifetime PTSD	rs9923585	Trend

Gene functional annotation

Gene related GO terms (count: 18)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0006766	vitamin metabolic process	biological process	TAS	7
GO:0016020	membrane	cellular component	IDA[19946888]	42
GO:0006810	transport	biological process	TAS[1360704]	8
GO:0005887	integral component of plasma membrane	cellular component	IEA	36
GO:0006691	leukotriene metabolic process	biological process	TAS	1
GO:0009235	cobalamin metabolic process	biological process	TAS	1
GO:0042493	response to drug	biological process	TAS[1360704]	25
GO:0005215	transporter activity	molecular function	TAS[1360704]	2
GO:0016887	ATPase activity	molecular function	IDA[15999530]	2
GO:0005886	plasma membrane	cellular component	IDA; TAS	99
GO:0044281	small molecule metabolic process	biological process	TAS	38
GO:0019369	arachidonic acid metabolic process	biological process	TAS	3
GO:0070062	extracellular exosome	cellular component	IDA[20458337]	58
GO:0005524	ATP binding	molecular function	IEA	23
GO:0055085	transmembrane transport	biological process	TAS	14
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	molecular function	IEA	1
GO:0016323	basolateral plasma membrane	cellular component	IDA[24130369]	6
GO:0006767	water-soluble vitamin metabolic process	biological process	TAS	1

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in PTSDgene
hsa02010	ABC transporters	1

Gene related interactors from protein-protein interactions data in PINA v2 (count: 22)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
ABCC1	TMEM173	No	--	association	21903422 , 21903422 , 21903422
ABCC1	ATP6V1H	No	biochemical	colocalization	22939629
ABCC1	STT3B	No	biochemical	colocalization	22939629
ABCC1	SAFB	No	biochemical	colocalization	22939629
ABCC1	TMOD2	No	biochemical	colocalization	22939629
ABCC1	RAVER1	No	biochemical	colocalization	22939629
ABCC1	TRAF3	No	--	--	21988832 , 21988832
ABCC1	PDCD6IP	No	biochemical	colocalization	22939629
ABCC1	RPS7	No	biochemical	colocalization	22939629
ABCC1	TMCO1	No	biochemical	colocalization	22939629
ABCC1	STX4	No	biochemical	colocalization	22939629
ABCC1	UNC93B1	No	--	--	21903422
ABCC1	VDAC3	No	biochemical	colocalization	22939629
ABCC1	MCU	No	biochemical	colocalization	22939629
ABCC1	NDUFB9	No	biochemical	colocalization	22939629
ABCC1	EIF3C	No	biochemical	colocalization	22939629
ABCC1	FKBP8	No	biochemical	colocalization	22939629
ABCC1	ATP6V1F	No	biochemical	colocalization	22939629
ABCC1	TMX2	No	biochemical	colocalization	22939629
ABCC1	NDUFAF3	No	biochemical	colocalization	22939629
ABCC1	MRPL17	No	biochemical	colocalization	22939629
ABCC1	PUF60	No	biochemical	colocalization	22939629