PTSDgene database

SNP Report

Basic Info
Name rs9817063 dbSNP Ensembl
Location 3:114128261 - 114128261(+)
Variant Seq C
Ancestral Allele T
Ref Seq T
Minor Allele Frequence 0.428115
Annotation downstream_gene_variant
Variant Effect downstream_gene_variant(ENST00000467632, ENST00000295881, ENST00000460779, ENST00000383673)
SIFT Annotation deleterious; tolerated
SIFT Variant Effect deleterious(ENST00000295881); tolerated(ENST00000460779, ENST00000383673, ENST00000467632)
PolyPhen Annotation benign; probably_damaging
PolyPhen Variant Effect benign(ENST00000295881); probably_damaging(ENST00000460779, ENST00000383673, ENST00000467632)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Enhancers
No. of Marker's Association Results 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Wolf, E. J.,2014 PTSD diagnosis In discovery sample: OR=1.427, uncorrected P-value= 0.007, ...... In discovery sample: OR=1.427, uncorrected P-value= 0.007, correct P-value=0.07 More... The SNP showed nominal evidence of association with lifetime...... The SNP showed nominal evidence of association with lifetime PTSD, In men showed nominally significant associations with PTSD again. More... Significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DRD3 dopamine receptor D3 3q13.3 2(1/1/0)

SNPs in LD with rs9817063 (count: 4)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 3)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx