SNP Report

Basic Info

Name	rs9817063 dbSNP Ensembl
Location	3:114128261 - 114128261(+)
Variant Seq	C
Ancestral Allele	T
Ref Seq	T
Minor Allele Frequence	0.428115
Annotation	downstream_gene_variant
Variant Effect	downstream_gene_variant(ENST00000467632, ENST00000295881, ENST00000460779, ENST00000383673)
SIFT Annotation	deleterious; tolerated
SIFT Variant Effect	deleterious(ENST00000295881); tolerated(ENST00000460779, ENST00000383673, ENST00000467632)
PolyPhen Annotation	benign; probably_damaging
PolyPhen Variant Effect	benign(ENST00000295881); probably_damaging(ENST00000460779, ENST00000383673, ENST00000467632)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Enhancers
No. of Marker's Association Results	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Wolf, E. J.,2014	PTSD diagnosis	In discovery sample: OR=1.427, uncorrected P-value= 0.007, ...... In discovery sample: OR=1.427, uncorrected P-value= 0.007, correct P-value=0.07 More...	The SNP showed nominal evidence of association with lifetime...... The SNP showed nominal evidence of association with lifetime PTSD, In men showed nominally significant associations with PTSD again. More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
DRD3	dopamine receptor D3	3q13.3	2(1/1/0)

SNPs in LD with rs9817063 (count: 4)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.


rs_ID	Annotation	No. of Association Results(Positive/Negative/Trend)	r²[population]
rs4646996	intron_variant(ENST00000460779, ENST00000467632, ENST00000383673, ENST00000295881)	1(1/0/0)	0.8989[EUR]

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs7632193	rs9817063 rs4646996	intron_variant	0.9893[EUR]
rs9845417	rs9817063 rs4646996	intron_variant	0.9893[EUR]
rs2399496	rs9817063 rs4646996	downstream_gene_variant	0.8847[EUR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx