SNP Report
Basic Info
| Name | rs737054 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 6:35607710 - 35607710(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.193091 | ||
| Annotation | non_coding_transcript_exon_variant; intron_variant; non_coding_transcript_variant | ||
| Variant Effect | non_coding_transcript_exon_variant(ENST00000407266); intron_variant(ENST00000542713, ENST00000539068, ENST00000357266, ENST00000536438); non_coding_transcript_variant(ENST00000407266) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000542713, ENST00000357266, ENST00000539068, ENST00000536438) | ||
| PolyPhen Annotation | probably_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000542713, ENST00000357266, ENST00000539068, ENST00000536438) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;Strong transcription;ZNF genes & repeats;Enhancers;Genic enhancers | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Binder, E. B.,2008 | PTSD Symptoms (PSS scores) | No available detail information. No available detail information. | We found no significant main effect of FKBP5 genotypes on PS...... We found no significant main effect of FKBP5 genotypes on PSS total score. More... | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Binder, E. B.,2008 | PTSD Symptoms (PSS scores) | Child abuse | No available detail information. No available detail information. | No significant signals was observed about this SNP's interac...... No significant signals was observed about this SNP's interaction of FKBP5 with child abuse to predict PTSD symptoms. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| FKBP5 | FK506 binding protein 5 | 6p21.31 | 25(12/13/0) |
SNPs in LD with rs737054 (count: 2)
Literature-origin SNPs (count: 0)
LD-proxies (count: 2)
SNP related eQTL (count: 1)