SNP Report
Basic Info
| Name | rs7300641 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 12:71974791 - 71974791(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | G | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.282548 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000333850) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000333850) | ||
| PolyPhen Annotation | possibly_damaging | ||
| PolyPhen Variant Effect | possibly_damaging(ENST00000333850) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Weak transcription;ZNF genes & repeats | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD severity | P-value=0.048 P-value=0.048 | Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| TPH2 | tryptophan hydroxylase 2 | 12q15 | 10(3/7/0) |
SNPs in LD with rs7300641 (count: 9)
Literature-origin SNPs (count: 0)
LD-proxies (count: 9)
SNP related eQTL (count: 1)