PTSDgene database

SNP Report

Basic Info
Name rs7076096 dbSNP Ensembl
Location 10:85848703 - 85848703(+)
Variant Seq T
Ancestral Allele T
Ref Seq C
Minor Allele Frequence 0.240216
Annotation intron_variant; NMD_transcript_variant
Variant Effect intron_variant(ENST00000464741, ENST00000327946, ENST00000536331); NMD_transcript_variant(ENST00000464741)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000536331, ENST00000464741, ENST00000327946)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000536331, ENST00000464741, ENST00000327946)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Xie, P.,2013 Lifetime PTSD Trauma Exposed African Americans: in GWAS,P-value=9.12E-06,i...... Trauma Exposed African Americans: in GWAS,P-value=9.12E-06,in replication,P-value=NT,in combined, P-value=NT. More... No significant signals were observed in the African American...... No significant signals were observed in the African American part of the sample. Genome-wide association study analyses restricted to trauma-exposed individuals yielded very similar results. More... Trend

SNP related genes (count: 2)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
GRID1 glutamate receptor, ionotropic, delta 1 10q22 Mapped by Literature SNP, Mapped by LD-proxy
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 9q34.3 1(0/0/1)

SNPs in LD with rs7076096 (count: 18)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 18)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-259G18.3 No Adipose Subcutaneous cis GTEx