SNP Report
Basic Info
| Name | rs4713916 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 6:35702206 - 35702206(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | G | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.222045 | ||
| Annotation | upstream_gene_variant; intron_variant | ||
| Variant Effect | upstream_gene_variant(ENST00000411131); intron_variant(ENST00000536438) | ||
| SIFT Annotation | deleterious; tolerated | ||
| SIFT Variant Effect | deleterious(ENST00000542713); tolerated(ENST00000539068, ENST00000357266, ENST00000536438) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000539068, ENST00000542713, ENST00000357266, ENST00000536438) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Binder, E. B.,2008 | PTSD Symptoms (PSS scores) | No available detail information. No available detail information. | We found no significant main effect of FKBP5 genotypes on PS...... We found no significant main effect of FKBP5 genotypes on PSS total score. More... | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Binder, E. B.,2008 | PTSD Symptoms (PSS scores) | Child abuse | No available detail information. No available detail information. | No significant signals was observed about this SNP's interac...... No significant signals was observed about this SNP's interaction of FKBP5 with child abuse to predict PTSD symptoms. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| FKBP5 | FK506 binding protein 5 | 6p21.31 | 25(12/13/0) |
SNPs in LD with rs4713916 (count: 16)
Literature-origin SNPs (count: 0)
LD-proxies (count: 16)
SNP related eQTL (count: 1)