SNP Report

Basic Info

Name	rs3093067 dbSNP Ensembl
Location	1:159712738 - 159712738(+)
Variant Seq	G
Ancestral Allele	A
Ref Seq	A
Minor Allele Frequence	0.0111821
Annotation	non_coding_transcript_exon_variant; 3_prime_UTR_variant; intron_variant; non_coding_transcript_variant
Variant Effect	non_coding_transcript_exon_variant(ENST00000473196, ENST00000489317); 3_prime_UTR_variant(ENST00000255030, ENST00000437342, ENST00000368112, ENST00000368110); intron_variant(ENST00000368111); non_coding_transcript_variant(ENST00000473196, ENST00000489317)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000255030)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000255030)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	lncRNA
Chromatin State	Active TSS;Enhancers
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Michopoulos, V.,2015	PTSD symptoms	T=1.31, P-value=0.19 T=1.31, P-value=0.19	No significant effect on PTSD symptoms. No significant effect on PTSD symptoms.	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
CRP	C-reactive protein, pentraxin-related	1q23.2	3(2/1/0)

SNPs in LD with rs3093067 (count: 1)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs3093064	rs3093067	upstream_gene_variant	0.9545[AFR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1	Yes	Adipose Subcutaneous	cis	GTEx