PTSDgene database

SNP Report

Basic Info
Name rs2862383 dbSNP Ensembl
Location 11:41802575 - 41802575(+)
Variant Seq G
Ancestral Allele T
Ref Seq T
Minor Allele Frequence 0.438698
Annotation downstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect downstream_gene_variant(ENST00000531247); intron_variant(ENST00000529282, ENST00000528720); non_coding_transcript_variant(ENST00000529282, ENST00000528720)
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000527150, ENST00000278198, ENST00000530763, ENST00000619527, ENST00000528697)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000527150, ENST00000278198, ENST00000530763, ENST00000619527, ENST00000528697)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ashley-Koch, A. E.,2015 Current PTSD In NHB subset: OR=1.64, main effect P-value=6.17E-06. In NHB subset: OR=1.64, main effect P-value=6.17E-06. This SNP was nominally significant with current PTSD among t...... This SNP was nominally significant with current PTSD among the NHB subset (P-value More... Trend
G*E study related association result (count: 2)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Ashley-Koch, A. E.,2015 Current PTSD Childhood trauma Logistic regression (additive genetic model) in NHB subset: ...... Logistic regression (additive genetic model) in NHB subset: snp and child trauma interaction P-value=0.15. More... We haven't observed significant evidence for gene*environmen...... We haven't observed significant evidence for gene*environment interactions of this snp with childhood trauma. More... Non-significant
Ashley-Koch, A. E.,2015 Current PTSD NTE (number of traumatic events) Logistic regression (additive genetic model) in NHB subset: ...... Logistic regression (additive genetic model) in NHB subset: snp and total trauma interaction P-value=0.50. More... We haven't observed significant evidence for gene*environmen...... We haven't observed significant evidence for gene*environment interactions of this snp with total trauma. More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
LINC01499 long intergenic non-protein coding RNA 1499 11p12 Mapped by Literature SNP, Mapped by LD-proxy

SNPs in LD with rs2862383 (count: 134)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 133)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx