SNP Report
Basic Info
| Name | rs2766581 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 6:35782522 - 35782522(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | A | ||
| Ref Seq | A | ||
| Minor Allele Frequence | 0.249201 | ||
| Annotation | downstream_gene_variant; upstream_gene_variant; intron_variant | ||
| Variant Effect | downstream_gene_variant(ENST00000403376, ENST00000360454, ENST00000481904, ENST00000467122); upstream_gene_variant(ENST00000428710); intron_variant(ENST00000373861) | ||
| SIFT Annotation | tolerated_-_low_confidence; tolerated | ||
| SIFT Variant Effect | tolerated_-_low_confidence(ENST00000360454); tolerated(ENST00000403376) | ||
| PolyPhen Annotation | probably_damaging; possibly_damaging | ||
| PolyPhen Variant Effect | probably_damaging(ENST00000403376); possibly_damaging(ENST00000360454) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | TF binding region;Chromatin interactive region | ||
| Chromatin State | Enhancers;Weak transcription | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD diagnosis | P-value=0.041 P-value=0.041 | Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 3)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| CLPSL1 | colipase like 1 | 6p21.31 | Mapped by Literature SNP, Mapped by LD-proxy |
| CLPSL2 | colipase like 2 | 6p21.31 | Mapped by Literature SNP, Mapped by LD-proxy |
| FKBP5 | FK506 binding protein 5 | 6p21.31 | 25(12/13/0) |
SNPs in LD with rs2766581 (count: 6)
Literature-origin SNPs (count: 0)
LD-proxies (count: 6)
SNP related eQTL (count: 1)