PTSDgene database

SNP Report

Basic Info
Name rs2284225 dbSNP Ensembl
Location 7:31098889 - 31098889(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.405551
Annotation intron_variant
Variant Effect intron_variant(ENST00000436116, ENST00000614107, ENST00000409363, ENST00000409489, ENST00000304166, ENST00000396211)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000614107, ENST00000409363, ENST00000396211, ENST00000304166, ENST00000409489)
PolyPhen Annotation probably_damaging
PolyPhen Variant Effect probably_damaging(ENST00000614107, ENST00000409363, ENST00000396211, ENST00000304166, ENST00000409489)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Strong transcription
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD severity P-value=0.304 P-value=0.304 Achieved nominal levels of significance with PTSD severity, ...... Achieved nominal levels of significance with PTSD severity, although was not significant after correction for multiple testing More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs2284225 (count: 8)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 7)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx