PTSDgene database

SNP Report

Basic Info
Name rs1541518 dbSNP Ensembl
Location 7:31108665 - 31108665(+)
Variant Seq T
Ancestral Allele T
Ref Seq G
Minor Allele Frequence 0.399161
Annotation downstream_gene_variant; 3_prime_UTR_variant
Variant Effect downstream_gene_variant(ENST00000409363, ENST00000409489, ENST00000396211, ENST00000436116); 3_prime_UTR_variant(ENST00000614107, ENST00000304166)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000436116, ENST00000614107, ENST00000304166, ENST00000409489, ENST00000396211, ENST00000409363)
PolyPhen Annotation probably_damaging; possibly_damaging
PolyPhen Variant Effect probably_damaging(ENST00000409489); possibly_damaging(ENST00000436116, ENST00000614107, ENST00000304166, ENST00000396211, ENST00000409363)
rSNP? Yes Link in rVarBase
Related Regulatory Elements lncRNA
Chromatin State Weak transcription;Strong transcription;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ressler, K. J.,2011 PTSD diagnosis Females: P-value=0.064, males: P-value=0.974 Females: P-value=0.064, males: P-value=0.974 No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs1541518 (count: 6)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 1)

LD-proxies (count: 5)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx