PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs2270025 dbSNP Ensembl
Location	7:30594388 - 30594388(+)
Variant Seq	C
Ancestral Allele	T
Ref Seq	T
Minor Allele Frequence	0.405351
Annotation	upstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect	upstream_gene_variant(ENST00000389266, ENST00000627489, LRG_243t1, ENST00000478124, ENST00000454308); intron_variant(ENST00000584199, ENST00000578994, ENST00000583664, ENST00000582549, ENST00000579174, ENST00000582733, ENST00000581794, ENST00000584372, ENST00000426529, ENST00000581665, ENST00000580440); non_coding_transcript_variant(ENST00000584199, ENST00000578994, ENST00000583664, ENST00000582549, ENST00000579174, ENST00000582733, ENST00000581794, ENST00000584372, ENST00000426529, ENST00000581665, ENST00000580440)
SIFT Annotation	deleterious_-_low_confidence; deleterious
SIFT Variant Effect	deleterious_-_low_confidence(ENST00000627489, ENST00000454308); deleterious(ENST00000389266, LRG_243t1)
PolyPhen Annotation	unknown; benign
PolyPhen Variant Effect	unknown(ENST00000627489, ENST00000454308); benign(ENST00000389266, LRG_243t1)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region;Chromatin interactive region
Chromatin State	Active TSS;Flanking Active TSS;Transcr. at gene 5' nd 3';Bivalent/Poised TSS
No. of Marker's Association Results	0 (Positive: 0; Negative: 0; Trend: 0)
Source	LD-proxy

SNP related association results

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
GARS	glycyl-tRNA synthetase	7p15	Mapped by LD-proxy, rSNP target
GGCT	gamma-glutamylcyclotransferase	7p15-p14	rSNP target
MTURN	maturin, neural progenitor differentiation regulator homolog (Xenopus)	7p15.1	rSNP target

SNPs in LD with rs2270025 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CAT	Yes	Adipose Subcutaneous	cis	GTEx