SNP Report
Basic Info
| Name | rs1386494 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 12:71958763 - 71958763(+) | ||
| Variant Seq | C | ||
| Ancestral Allele | T | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.143171 | ||
| Annotation | intron_variant; non_coding_transcript_variant | ||
| Variant Effect | intron_variant(ENST00000546576, ENST00000333850); non_coding_transcript_variant(ENST00000546576) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000333850) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000333850) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Enhancers;Flanking Active TSS | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Goenjian, A. K.,2012 | PTSD-RI (PTSD symptoms) | After adjusting for age, sex, exposure and environmental var...... After adjusting for age, sex, exposure and environmental variables, analyses of PTSD-RI and this SNP: P-value>0.05. More... | The remainder of the TPH2 SNPs tested did not show a signifi...... The remainder of the TPH2 SNPs tested did not show a significant association with PTSD-RI scores; and the linkage scores were below 1.0. More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| TPH2 | tryptophan hydroxylase 2 | 12q15 | 10(3/7/0) |
SNPs in LD with rs1386494 (count: 33)
Literature-origin SNPs (count: 0)
LD-proxies (count: 33)
SNP related eQTL (count: 1)