PTSDgene database

SNP Report

Basic Info
Name rs10226318 dbSNP Ensembl
Location 7:31057843 - 31057843(+)
Variant Seq G
Ancestral Allele G
Ref Seq T
Minor Allele Frequence 0.366813
Annotation intron_variant
Variant Effect intron_variant(ENST00000409363, ENST00000304166, ENST00000614107, ENST00000431811)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000326139, ENST00000409904)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000326139, ENST00000409904)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Active TSS;Enhancers;Bivalent Enhancer
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Solovieff, N.,2014 PTSD diagnosis P-value=0.161 P-value=0.161 Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... Non-significant


SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 7p14.3 19(8/11/0)

SNPs in LD with rs10226318 (count: 6)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 6)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx