SNP Report
Basic Info
| Name | rs10226318 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 7:31057843 - 31057843(+) | ||
| Variant Seq | G | ||
| Ancestral Allele | G | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.366813 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000409363, ENST00000304166, ENST00000614107, ENST00000431811) | ||
| SIFT Annotation | deleterious | ||
| SIFT Variant Effect | deleterious(ENST00000326139, ENST00000409904) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000326139, ENST00000409904) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | Chromatin interactive region | ||
| Chromatin State | Weak transcription;Active TSS;Enhancers;Bivalent Enhancer | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Solovieff, N.,2014 | PTSD diagnosis | P-value=0.161 P-value=0.161 | Achieved nominal levels of significance with PTSD diagnosis,...... Achieved nominal levels of significance with PTSD diagnosis, although was not significant after correction for multiple testing More... | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| ADCYAP1R1 | adenylate cyclase activating polypeptide 1 (pituitary) receptor type I | 7p14.3 | 19(8/11/0) |
SNPs in LD with rs10226318 (count: 6)
Literature-origin SNPs (count: 0)
LD-proxies (count: 6)
SNP related eQTL (count: 1)