PTSDgene database

Study Report

Study Information
Basic Info
Citation Voisey, J., et al. (2010). "A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia." Behav Brain Funct 6: 41.
Phenotype PTSD
Trauma Vietnam combat
Study Design Case-control
Study Type Candidate gene association study
Sample Size 127 cases, 250 controls
SNP/Marker Size 1 SNP
Predominant Ethnicity Caucasian
Population Australian
Gender Case: not mentioned, Control: 148 males and 102 females
Age Case: mean age= 52.3 years, SD=6.1, Control: mean age=36.8 years, SD=12.8 years

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs9370822 PTSD DTNBP1 Allele frequencies: Pearson's chi-square test: X2= 12.603, P-value= 0.0004, Odd's ratio (95% CI): 1.78(1.28-2.50), Genotype frequencies: Pearson's chi-square test: P-value= 0.002, Mantel-Haenszel chi-square test for trend: P-value= 0.0004 The SNP was found to be associated with PTSD both at the all...... The SNP was found to be associated with PTSD both at the allel level and genotype level. Individuals with PTSD were more than three times as likely to carry the CC genotype compared to the AA genotype. More... Significant