PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

Study Report

Study Information

Basic Info

Reference	Miller, M. W.,2018 PMID: 28867284
Citation	Miller, M. W., et al. (2018). "CRP polymorphisms and DNA methylation of the AIM2 gene influence associations between trauma exposure, PTSD, and C-reactive protein." Brain Behav Immun 67: 194-202.
Phenotype	Current PTSD severity
Trauma	Combat
Study Design	Cross-sectional study
Study Type	Candidate gene association study, Gene-environment interaction study
Sample Size	286 samples
SNP/Marker Size	1 SNP
Predominant Ethnicity	Caucasian
Population	American
Gender	88.5% males, 11.5% females
Age	Mean age=31 years,SD=9

Detail Info

Genetic result reported by this study

Normal genetic result reported by this study (count: 1)

Marker	Phenotype	Related Gene	Statistical Values	Author Comments	Marker's Category
rs3091244	Current PTSD severity	CRP	B=0.062, P-value=0.334	Main effect of this SNP is not significant. Main effect of this SNP is not significant.	Non-significant

Gene * Environment result reported by this study (count: 1)

Marker	Phenotype	Related Gene	Environment	Statistical Values	Author Comments	Marker's Category
rs3091244	Current PTSD severity	CRP	Lifetime trauma exposure	B=2.756, P-value=0.006	Rs3091244 moderated the association between lifetime trauma ...... Rs3091244 moderated the association between lifetime trauma exposure and current PTSD severity. More...	Significant