PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Miller, M. W., et al. (2018). "CRP polymorphisms and DNA methylation of the AIM2 gene influence associations between trauma exposure, PTSD, and C-reactive protein." Brain Behav Immun 67: 194-202.
Phenotype Current PTSD severity
Trauma Combat
Study Design Cross-sectional study
Study Type Candidate gene association study, Gene-environment interaction study
Sample Size 286 samples
SNP/Marker Size 1 SNP
Predominant Ethnicity Caucasian
Population American
Gender 88.5% males, 11.5% females
Age Mean age=31 years,SD=9

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
rs3091244 Current PTSD severity CRP B=0.062, P-value=0.334 Main effect of this SNP is not significant. Main effect of this SNP is not significant. Non-significant

Gene * Environment result reported by this study (count: 1)
Marker Phenotype Related Gene Environment Statistical Values Author Comments Marker's Category
rs3091244 Current PTSD severity CRP Lifetime trauma exposure B=2.756, P-value=0.006 Rs3091244 moderated the association between lifetime trauma ...... Rs3091244 moderated the association between lifetime trauma exposure and current PTSD severity. More... Significant