Study Report
Study Information
Basic Info
| Reference |
Hauser, M. A.,2017 PMID: 27701011
|
| Citation |
Hauser, M. A., et al. (2017). "Further evidence for a role of the ADRB2 gene in risk for posttraumatic stress disorder." J Psychiatr Res 84: 59-61. |
| Phenotype |
Current PTSD diagnosis |
| Trauma |
Various |
| Study Design |
Cross-sectional study |
| Study Type |
Candidate gene association study, Gene-environment interaction study |
| Sample Size |
1708 samples |
| SNP/Marker Size |
1 SNP |
| Predominant Ethnicity |
Black, Caucasian |
| Population |
American |
| Gender |
1304 males, 404 females |
| Age |
NHB cohort: mean age=39.06 years, SD=9.73, NHW cohort: mean age=36.28 years, SD=10.44. |
Detail Info
| Sample Diagnosis |
DSM-IV |
| Related Diagnostic Tools |
Structured Clinical Interview for DSM-IV Disorders (SCID), Clinician-Administered PTSD Scale (CAPS) |
| Sample Status |
Lifetime MDD diagnosis: NHB cohort: 40.5%, NHW cohort: 40.28%. Lifetime substence abuse: NHB cohort: 21.95%, NHW cohort: 18.60%. Lifetime MDD diagnosis: NHB cohort: 40.13%, NHW cohort: 44.34%. |
| Controls Exposed |
NA |
| Replication Size |
None |
| Result Summary |
The findings from the present research provide continued support for the interaction of rs2400707, and other SNPs within the ADRB2 gene, with childhood trauma in relation to risk for PTSD. |
| Potential Biomarker |
None |
Genetic result reported by this study
