Study Report
Study Information
Basic Info
| Reference |
Sadeh, N.,2016 PMID: 27038412
|
| Citation |
Sadeh, N., et al. (2016). "Epigenetic Variation at Ska2 Predicts Suicide Phenotypes And Internalizing Psychopathology." Depress Anxiety 33(4): 308-315. |
| Phenotype |
PTSD symptoms, PTSD diagnosis |
| Trauma |
Various |
| Study Design |
Cross-sectional study |
| Study Type |
Candidate gene association study |
| Sample Size |
466 samples |
| SNP/Marker Size |
1 SNP |
| Predominant Ethnicity |
Caucasian |
| Population |
American |
| Gender |
302 males, 164 females |
| Age |
Mean age=52.4 years,SD=10.7 |
Detail Info
| Sample Diagnosis |
DSM-IV |
| Related Diagnostic Tools |
Clinician Administered PTSD Scale (CAPS), Structured Clinical Interview for DSM-IV (SCID-IV) |
| Sample Status |
The sample consisted of 466 White, non-Hispanic military veterans and their cohabitating intimate partners (veterans=73%, partners=27%). Both current and lifetime PTSD were measured. 55% with MDD, 17% with dysthymia, 11% with GAD. |
| Controls Exposed |
NA |
| Replication Size |
None |
| Result Summary |
Genetic variation at the methylation-associated SNP (rs7208505) was not related to any of the phenotypes examined. |
| Potential Biomarker |
None |
Genetic result reported by this study
Normal genetic result reported by this study (count: 2)
| Marker |
Phenotype |
Related Gene |
Statistical Values |
Author Comments |
Marker's Category |
|
rs7208505
|
PTSD symptoms |
SKA2 |
B<0.05,P-value>0.66 |
SKA2 genotype was also not a significant predictor of PTSD s......
SKA2 genotype was also not a significant predictor of PTSD symptoms.
More...
|
Non-significant |
|
rs7208505
|
PTSD diagnosis |
SKA2 |
Wald X2<0.99,P-value>0.32 |
SKA2 genotype was also not a significant predictor of PTSD d......
SKA2 genotype was also not a significant predictor of PTSD diagnosis.
More...
|
Non-significant |
