PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs9804190 dbSNP Ensembl
Location	10:60080073 - 60080073(+)
Variant Seq	T
Ancestral Allele	T
Ref Seq	C
Minor Allele Frequence	0.257788
Annotation	downstream_gene_variant; upstream_gene_variant; intron_variant
Variant Effect	downstream_gene_variant(ENST00000508449, ENST00000622427); upstream_gene_variant(ENST00000365320); intron_variant(ENST00000280772, ENST00000503366, ENST00000511043, ENST00000616444, ENST00000373820, ENST00000373827, ENST00000618374, ENST00000355288, ENST00000610321)
SIFT Annotation	deleterious_-_low_confidence
SIFT Variant Effect	deleterious_-_low_confidence(ENST00000610321, ENST00000280772)
PolyPhen Annotation	benign; possibly_damaging
PolyPhen Variant Effect	benign(ENST00000610321); possibly_damaging(ENST00000280772)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Strong transcription
No. of Marker's Association Results	1 (Positive: 1; Negative: 0; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Logue, M. W.,2013	PTSD	OR=0.71, P-value=0.042, corrected P-value=0.93 OR=0.71, P-value=0.042, corrected P-value=0.93	The bipolar disorder-associated SNP rs9804190 was the only S...... The bipolar disorder-associated SNP rs9804190 was the only SNPin ANK3 that was nominally significantly associated (P-value< 0.05) with both PTSD and externalizing. More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	2(2/0/0)

SNPs in LD with rs9804190 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
RP11-259G18.3	No	Adipose Subcutaneous	cis	GTEx