SNP Report
Basic Info
| Name | rs963468 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 3:114144040 - 114144040(+) | ||
| Variant Seq | A | ||
| Ancestral Allele | G | ||
| Ref Seq | G | ||
| Minor Allele Frequence | 0.272165 | ||
| Annotation | intron_variant | ||
| Variant Effect | intron_variant(ENST00000295881, ENST00000467632, ENST00000460779, ENST00000383673) | ||
| SIFT Annotation | tolerated | ||
| SIFT Variant Effect | tolerated(ENST00000467632, ENST00000295881, ENST00000460779, ENST00000383673) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000467632, ENST00000295881, ENST00000460779, ENST00000383673) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | n/a | ||
| Chromatin State | Enhancers | ||
| No. of Marker's Association Results | 1 (Positive: 1; Negative: 0; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Wolf, E. J.,2014 | PTSD diagnosis | In discovery sample: OR=1.457, uncorrected P-value= 0.005, ...... In discovery sample: OR=1.457, uncorrected P-value= 0.005, correct P-value=0.051 More... | The SNP showed nominal evidence of association with lifetime...... The SNP showed nominal evidence of association with lifetime PTSD, In men showed nominally significant associations with PTSD again. More... | Significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| DRD3 | dopamine receptor D3 | 3q13.3 | 2(1/1/0) |
SNPs in LD with rs963468 (count: 2)
Literature-origin SNPs (count: 0)
LD-proxies (count: 2)
SNP related eQTL (count: 1)