PTSDgene database

SNP Report

Basic Info
Name rs9538394 dbSNP Ensembl
Location 13:59354287 - 59354287(+)
Variant Seq T
Ancestral Allele T
Ref Seq G
Minor Allele Frequence 0.457069
Annotation downstream_gene_variant
SIFT Annotation deleterious_-_low_confidence
SIFT Variant Effect deleterious_-_low_confidence(ENST00000612954, ENST00000377918)
PolyPhen Annotation possibly_damaging; probably_damaging
PolyPhen Variant Effect possibly_damaging(ENST00000377918); probably_damaging(ENST00000612954)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Weak transcription;Active TSS;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Xie, P.,2013 Lifetime PTSD Trauma Exposed European Americans: in GWAS,P-value=9.12E-06,...... Trauma Exposed European Americans: in GWAS,P-value=9.12E-06,in replication,P-value=NT,in combined, P-value=NT. More... No significant signals was observed about this SNP. Genome-w...... No significant signals was observed about this SNP. Genome-wide association study analyses restricted to trauma-exposed individuals yielded very similar results. More... Trend

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DIAPH3 diaphanous related formin 3 13q21.2 1(0/0/1)

SNPs in LD with rs9538394 (count: 1)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx