Gene Report

Basic Info

Approved Symbol	DIAPH3
Previous Symbol	AUNA1
Symbol Alias	"DRF3\|FLJ34705\|AN\|NSDAN"
Approved Name	diaphanous related formin 3
Previous Name	"diaphanous (Drosophila, homolog) 3\|auditory neuropathy, autosomal dominant 1\|diaphanous homolog 3 (Drosophila)"
Location	13q21.2
Position	chr13:59665583-60163987, -1
External Links	HGNC: 15480 Entrez Gene: 81624 Ensembl: ENSG00000139734 UCSC: uc001vht.5
No. of Association Results	1 (Positive: 0; Negative: 0; trend: 1)
Annotation Type	Literature-origin

Gene related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Marker	Gene's Category
Xie, P.,2013	Lifetime PTSD	rs9538394	Trend

Gene functional annotation

Gene related GO terms (count: 7)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0003779	actin binding	molecular function	IEA	3
GO:0030036	actin cytoskeleton organization	biological process	IEA	3
GO:0017048	Rho GTPase binding	molecular function	IEA	1
GO:0007283	spermatogenesis	biological process	IEA	7
GO:0007264	small GTPase mediated signal transduction	biological process	TAS	14
GO:0005634	nucleus	cellular component	IEA	81
GO:0005829	cytosol	cellular component	TAS	78

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in PTSDgene
hsa04810	Regulation of actin cytoskeleton	2

Gene related interactors from protein-protein interactions data in PINA v2 (count: 3)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
DIAPH3	WWOX	No	--	--	24550385
DIAPH3	HDAC6	No	--	--	15976449
DIAPH3	NCKIPSD	No	--	--	11509578 , 11509578 , 11509578