SNP Report

Basic Info

Name	rs61793204 dbSNP Ensembl
Location	4:31288660 - 31288660(+)
Variant Seq	A
Ancestral Allele	T
Ref Seq	G
Minor Allele Frequence	0.192093
Annotation	downstream_gene_variant
SIFT Annotation	deleterious; tolerated
SIFT Variant Effect	deleterious(ENST00000621961); tolerated(ENST00000511884)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000511884, ENST00000621961)
rSNP?	No Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Inactive region
No. of Marker's Association Results	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Ashley-Koch, A. E.,2015	Current PTSD	In NHW subset: OR=0.40, main effect P-value=8.60E-06. In NHW subset: OR=0.40, main effect P-value=8.60E-06.	This SNP was nominally significant with current PTSD among t...... This SNP was nominally significant with current PTSD among the NHW subset (P-value More...	Trend

G*E study related association result (count: 2)

Reference	Phenotype	Environment	Statistical Values	Author Comments	Marker's Category
Ashley-Koch, A. E.,2015	Current PTSD	Childhood trauma	Logistic regression (additive genetic model) in NHW subset: ...... Logistic regression (additive genetic model) in NHW subset: snp and child trauma interaction P-value=0.86. More...	We haven't observed significant evidence for geneenvironmen...... We haven't observed significant evidence for geneenvironment interactions of this snp with childhood trauma. More...	Non-significant
Ashley-Koch, A. E.,2015	Current PTSD	NTE (number of traumatic events)	Logistic regression (additive genetic model) in NHW subset: ...... Logistic regression (additive genetic model) in NHW subset: snp and total trauma interaction P-value=0.82. More...	We haven't observed significant evidence for geneenvironmen...... We haven't observed significant evidence for geneenvironment interactions of this snp with total trauma. More...	Non-significant

SNP related genes (count: 0)

SNPs in LD with rs61793204 (count: 128)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 128)

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs61795437	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8042[AFR]; 0.9377[AMR]
rs57058567	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8671[AFR]; 1.0000[AMR]
rs11944687	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219152	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793175	rs61793204	downstream_gene_variant	0.9563[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs4435703	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793174	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793184	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793185	rs61793204	downstream_gene_variant	0.9563[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219149	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9185[AFR]
rs61793197	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793246	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8144[AFR]; 1.0000[AMR]
rs7675010	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs4532198	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs11735188	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 0.9377[AMR]
rs61793199	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219161	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9185[AFR]
rs61793189	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs56297125	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795439	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9377[AMR]
rs4475106	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795434	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8775[AFR]
rs73219154	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs59824229	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793192	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs55758619	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs61793168	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11724139	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs61793181	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8671[AFR]; 1.0000[AMR]
rs73219142	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs73219139	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11728603	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8303[AFR]; 1.0000[AMR]
rs61793236	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs61793176	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11734171	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8230[AFR]
rs4494995	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11724255	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs73219151	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs58612211	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs55709280	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9185[AFR]
rs61793190	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs59278732	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs61793179	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793253	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8769[AFR]
rs61795440	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 0.9377[AMR]
rs11727096	rs61793204	downstream_gene_variant	0.9564[EUR]; 0.9126[AMR]
rs60685631	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 0.9692[AMR]
rs7661417	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs57097128	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs61509951	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs56132097	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9175[AFR]
rs61793167	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs4594682	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9185[AFR]
rs59535561	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793200	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8042[AFR]; 1.0000[AMR]
rs61793198	rs61793204	downstream_gene_variant	0.9287[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs59805890	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793241	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs10939333	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793180	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219141	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs7676585	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs56105245	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs61793186	rs61793204	downstream_gene_variant	0.9563[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793244	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9175[AFR]
rs7683013	rs61793204	downstream_gene_variant	0.9564[EUR]; 0.8506[AFR]; 0.9402[AMR]
rs73219147	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219145	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61414179	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11938890	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8144[AFR]; 1.0000[AMR]
rs61793173	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs6448759	rs61793204	downstream_gene_variant	0.8168[AFR]
rs59716046	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793191	rs61793204	downstream_gene_variant	0.9708[EUR]; 1.0000[AMR]
rs4466011	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793177	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs58119181	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs56338318	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs73219164	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9586[AFR]
rs11946227	rs61793204	downstream_gene_variant	0.8134[EUR]
rs61793254	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8769[AFR]
rs60139026	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8842[AFR]; 1.0000[AMR]
rs4420939	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs56183366	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs59001602	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs56082826	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11944890	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219155	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11731067	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8264[AFR]; 1.0000[AMR]
rs11729851	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 0.9377[AMR]
rs61793178	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs10939335	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs7676287	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9586[AFR]
rs61793169	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs73219160	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793201	rs61793204	downstream_gene_variant	0.9274[EUR]; 0.9126[AMR]
rs10939334	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793193	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795438	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 0.9377[AMR]
rs61793170	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs7699876	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs7676813	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs4404505	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795436	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8775[AFR]
rs61793247	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9175[AFR]
rs4371575	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795432	rs61793204	downstream_gene_variant	0.8168[AFR]
rs61555142	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9126[AMR]
rs61793188	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793196	rs61793204	downstream_gene_variant	0.9708[EUR]; 1.0000[AMR]
rs61429152	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795444	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61793195	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs57961387	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61795435	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.8775[AFR]
rs73219165	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9185[AFR]
rs73219162	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8506[AFR]; 1.0000[AMR]
rs11935557	rs61793204	downstream_gene_variant	0.9130[EUR]; 0.8192[AFR]; 0.9685[AMR]
rs59499969	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs11734175	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.9087[AMR]
rs58121827	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs11725352	rs61793204	downstream_gene_variant	0.8168[AFR]
rs61793202	rs61793204	downstream_gene_variant	0.9274[EUR]; 0.8100[AFR]; 1.0000[AMR]
rs73219168	rs61793204	downstream_gene_variant	0.8134[EUR]; 0.9175[AFR]
rs60747279	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs73219148	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]
rs61701439	rs61793204	downstream_gene_variant	0.9563[EUR]; 0.8347[AFR]; 1.0000[AMR]
rs73219140	rs61793204	downstream_gene_variant	0.9708[EUR]; 0.8192[AFR]; 1.0000[AMR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1-IT1	Yes	Adipose Subcutaneous	cis	GTEx