PTSDgene database

SNP Report

Basic Info
Name rs2853550 dbSNP Ensembl
Location 2:112829544 - 112829544(+)
Variant Seq G
Ancestral Allele G
Ref Seq A
Minor Allele Frequence 0.202476
Annotation downstream_gene_variant
Variant Effect downstream_gene_variant(ENST00000418817, ENST00000491056, ENST00000416750, ENST00000263341, ENST00000487639, ENST00000432018, ENST00000496280)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000263341)
PolyPhen Annotation possibly_damaging
PolyPhen Variant Effect possibly_damaging(ENST00000263341)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription;Strong transcription;Genic enhancers;Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Hovhannisyan, L.,2017 PTSD diagnosis A carriage: OR=0.71, P-value=0.17, corrected P-value=0.85 A carriage: OR=0.71, P-value=0.17, corrected P-value=0.85 No association between this SNP and PTSD was found. No association between this SNP and PTSD was found. Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
IL1B interleukin 1 beta 2q14 1(1/0/0)

SNPs in LD with rs2853550 (count: 4)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 4)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx