SNP Report
Basic Info
| Name | rs25531 dbSNP Ensembl | ||
|---|---|---|---|
| Location | 17:30237328 - 30237328(+) | ||
| Variant Seq | C | ||
| Ancestral Allele | T | ||
| Ref Seq | T | ||
| Minor Allele Frequence | 0.13758 | ||
| Annotation | upstream_gene_variant | ||
| Variant Effect | upstream_gene_variant(ENST00000577420, ENST00000394821, ENST00000401766, ENST00000261707) | ||
| SIFT Annotation | deleterious_-_low_confidence | ||
| SIFT Variant Effect | deleterious_-_low_confidence(ENST00000261714) | ||
| PolyPhen Annotation | benign | ||
| PolyPhen Variant Effect | benign(ENST00000261714) | ||
| rSNP? | Yes Link in rVarBase | ||
| Related Regulatory Elements | TF binding region | ||
| Chromatin State | Bivalent/Poised TSS;Bivalent Enhancer;Enhancers;Weak transcription;Active TSS | ||
| No. of Marker's Association Results | 1 (Positive: 0; Negative: 1; Trend: 0) | ||
| Source | Literature | ||
SNP related association results
| Reference | Phenotype | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|
| Mercer, K. B.,2012 | Postshooting PTSD symptoms score (delta DEQ >1 month) | In all races or white participants only, rs25531 genotype P-...... In all races or white participants only, rs25531 genotype P-value>0.05. More... | We did not observe main effects for rs25531 alone on PTSD sy...... We did not observe main effects for rs25531 alone on PTSD symptom score (>1 month delta DEQ). More... | Non-significant |
G*E study related association result (count: 1)
| Reference | Phenotype | Environment | Statistical Values | Author Comments | Marker's Category |
|---|---|---|---|---|---|
| Mercer, K. B.,2012 | Postshooting PTSD symptoms score (delta DEQ >1 month) | Shooting exposure | White participants only: P-value>0.01. White participants only: P-value>0.01. | Not significant. Not significant. | Non-significant |
SNP related genes (count: 1)
| Approved Symbol | Approved Name | Location | No. of Association Results (Positive/Negative/Trend)  |
|---|---|---|---|
| SLC6A4 | solute carrier family 6 (neurotransmitter transporter), member 4 | 17q11.2 | 44(13/31/0) |
SNPs in LD with rs25531 (count: 0)
SNP related eQTL (count: 1)