PTSDgene database

SNP Report

Basic Info
Name rs2267717 dbSNP Ensembl
Location 7:30677427 - 30677427(+)
Variant Seq A
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.241613
Annotation downstream_gene_variant; intron_variant; NMD_transcript_variant
Variant Effect downstream_gene_variant(ENST00000445981, ENST00000423776); intron_variant(ENST00000471646, ENST00000341843, ENST00000506074, ENST00000348438, ENST00000452278); NMD_transcript_variant(ENST00000452278)
SIFT Annotation tolerated_-_low_confidence; tolerated
SIFT Variant Effect tolerated_-_low_confidence(ENST00000506074); tolerated(ENST00000471646)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000506074, ENST00000471646)
rSNP? Yes Link in rVarBase
Related Regulatory Elements Chromatin interactive region
Chromatin State Weak transcription
No. of Marker's Association Results 1 (Positive: 1; Negative: 0; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Wolf, E. J.,2013 PTSD diagnosis OR=0.64, 95% CI: 0.43-0.95, P-value uncorrected=0.03, P-valu...... OR=0.64, 95% CI: 0.43-0.95, P-value uncorrected=0.03, P-value corrected=0.34 More... It showed nominally significant associations with lifetime P...... It showed nominally significant associations with lifetime PTSD diagnosis, but didn't pass the multiple testing. More... Significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
CRHR2 corticotropin releasing hormone receptor 2 7p14.3 2(2/0/0)

SNPs in LD with rs2267717 (count: 0)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
LRRC37A4P No Adipose Subcutaneous cis GTEx