PTSDgene database

SNP Report

Basic Info
Name rs17504106 dbSNP Ensembl
Location 5:161042632 - 161042632(+)
Variant Seq C
Ancestral Allele G
Ref Seq G
Minor Allele Frequence 0.139976
Annotation upstream_gene_variant
SIFT Annotation tolerated
SIFT Variant Effect tolerated(ENST00000327245)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000327245)
rSNP? Yes Link in rVarBase
Related Regulatory Elements n/a
Chromatin State Enhancers
No. of Marker's Association Results 1 (Positive: 0; Negative: 0; Trend: 1)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Ashley-Koch, A. E.,2015 Current PTSD In NHB subset: OR=2.97, main effect P-value=4.72E-06. In NHB subset: OR=2.97, main effect P-value=4.72E-06. This SNP was nominally significant with current PTSD among t...... This SNP was nominally significant with current PTSD among the NHB subset (P-value More... Trend
G*E study related association result (count: 2)
Reference Phenotype Environment Statistical Values Author Comments Marker's Category
Ashley-Koch, A. E.,2015 Current PTSD Childhood trauma Logistic regression (additive genetic model) in NHB subset: ...... Logistic regression (additive genetic model) in NHB subset: snp and child trauma interaction P-value=0.37. More... We haven't observed significant evidence for gene*environmen...... We haven't observed significant evidence for gene*environment interactions of this snp with childhood trauma. More... Non-significant
Ashley-Koch, A. E.,2015 Current PTSD NTE (number of traumatic events) Logistic regression (additive genetic model) in NHB subset: ...... Logistic regression (additive genetic model) in NHB subset: snp and total trauma interaction P-value=0.02. More... Among the NHB, we observed nominally significant interaction...... Among the NHB, we observed nominally significant interactions with total trauma for this snp. More... Non-significant


SNP related genes (count: 0)

SNPs in LD with rs17504106 (count: 44)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 44)


SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
CRHR1-IT1 Yes Adipose Subcutaneous cis GTEx