PTSDgene database

SNP Report

Basic Info
Name rs1611115 dbSNP Ensembl
Location 9:133635393 - 133635393(+)
Variant Seq C
Ancestral Allele C
Ref Seq T
Minor Allele Frequence 0.21266
Annotation upstream_gene_variant
Variant Effect upstream_gene_variant(ENST00000393056, ENST00000564021, ENST00000263611)
SIFT Annotation deleterious
SIFT Variant Effect deleterious(ENST00000393056, ENST00000263611)
PolyPhen Annotation benign
PolyPhen Variant Effect benign(ENST00000393056, ENST00000263611)
rSNP? Yes Link in rVarBase
Related Regulatory Elements TF binding region
Chromatin State Weak transcription;Enhancers;Bivalent Enhancer
No. of Marker's Association Results 1 (Positive: 0; Negative: 1; Trend: 0)
Source Literature

SNP related association results
Normal genetic study related association results (count: 1)
Reference Phenotype Statistical Values Author Comments Marker's Category
Mustapic, M.,2007 Chronic PTSD Genotype frequencies: X2=2.30; df=2; P-value=0.3...... Genotype frequencies: X2=2.30; df=2; P-value=0.32; allele frequencies: X2=2.01; df=1; P-value=0.156. More... rs1611115, DBH genotype and allele frequencies were similarl...... rs1611115, DBH genotype and allele frequencies were similarly distributed between the two groups of war veterans. More... Non-significant

SNP related genes (count: 1)
Approved Symbol Approved Name Location No. of Association Results (Positive/Negative/Trend)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 4(0/4/0)

SNPs in LD with rs1611115 (count: 1)
The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r2<=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 1)

SNP related eQTL (count: 1)
Gene Symbol Gene Existed in PTSDgene? Tissue Trans/Cis Source
RP11-707O23.5 No Adipose Subcutaneous cis GTEx