PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs12051897 dbSNP Ensembl
Location	17:59130179 - 59130179(+)
Variant Seq	A
Ancestral Allele	G
Ref Seq	G
Minor Allele Frequence	0.460264
Annotation	upstream_gene_variant; intron_variant; NMD_transcript_variant; non_coding_transcript_variant
Variant Effect	upstream_gene_variant(ENST00000516403); intron_variant(ENST00000437036, ENST00000330137, ENST00000578519, ENST00000581068, ENST00000583927, ENST00000583976, ENST00000584089, ENST00000578105, ENST00000583380, ENST00000580541); NMD_transcript_variant(ENST00000578519, ENST00000583976); non_coding_transcript_variant(ENST00000583927)
SIFT Annotation	tolerated_-_low_confidence; tolerated
SIFT Variant Effect	tolerated_-_low_confidence(ENST00000583976, ENST00000437036); tolerated(ENST00000581068, ENST00000578519, ENST00000584089, ENST00000330137, ENST00000583380)
PolyPhen Annotation	unknown; benign
PolyPhen Variant Effect	unknown(ENST00000583976, ENST00000437036); benign(ENST00000581068, ENST00000578519, ENST00000584089, ENST00000330137, ENST00000583380)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	Chromatin interactive region
Chromatin State	Weak transcription;Strong transcription
No. of Marker's Association Results	0 (Positive: 0; Negative: 0; Trend: 0)
Source	LD-proxy

SNP related association results

SNP related genes (count: 4)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
RNU2-58P	RNA, U2 small nuclear 58, pseudogene	17q22	Mapped by LD-proxy
SMG8	SMG8 nonsense mediated mRNA decay factor	17q23.2	rSNP target
PRR11	proline rich 11	17q23.2	rSNP target
SKA2	spindle and kinetochore associated complex subunit 2	17q23.2	2(0/2/0)

SNPs in LD with rs12051897 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
CRHR1	Yes	Adipose Subcutaneous	cis	GTEx