SNP Report

Basic Info

Name	rs11979764 dbSNP Ensembl
Location	7:31091739 - 31091739(+)
Variant Seq	A
Ancestral Allele	A
Ref Seq	C
Minor Allele Frequence	0.122005
Annotation	intron_variant
Variant Effect	intron_variant(ENST00000409363, ENST00000304166, ENST00000409489, ENST00000614107, ENST00000396211, ENST00000436116)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000409363, ENST00000304166, ENST00000614107, ENST00000396211, ENST00000409489)
PolyPhen Annotation	benign; probably_damaging
PolyPhen Variant Effect	benign(ENST00000304166, ENST00000614107, ENST00000396211, ENST00000409489); probably_damaging(ENST00000409363)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	n/a
Chromatin State	Weak transcription;Enhancers
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Ressler, K. J.,2011	PTSD diagnosis	Females: P-value=0.508, males: P-value=0.565 Females: P-value=0.508, males: P-value=0.565	No significant result in females or males after multiple cor...... No significant result in females or males after multiple corrections. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
ADCYAP1R1	adenylate cyclase activating polypeptide 1 (pituitary) receptor type I	7p14.3	19(8/11/0)

SNPs in LD with rs11979764 (count: 3)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs6965700	rs11979764	intron_variant	0.9305[AFR]
rs11978620	rs11979764	intron_variant	0.9000[AFR]
rs11979753	rs11979764	intron_variant	0.9899[AFR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
LRRC37A4P	No	Adipose Subcutaneous	cis	GTEx