Gene Report

Basic Info

Approved Symbol	TBC1D2
Symbol Alias	"PARIS1\|TBC1D2A\|Armus"
Approved Name	TBC1 domain family member 2
Previous Name	TBC1 domain family, member 2
Name Alias	prostate antigen recognized and identified by SEREX
Location	9q22.32
Position	chr9:98198999-98255721, -1
External Links	HGNC: 18026 Entrez Gene: 55357 Ensembl: ENSG00000095383 UCSC: uc011lvb.2
No. of Association Results	1 (Positive: 0; Negative: 0; trend: 1)
Annotation Type	Literature-origin, Mapped by Literature SNP, Mapped by LD-proxy

Gene related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Marker	Gene's Category
Ashley-Koch, A. E.,2015	Current PTSD	rs7866350	Trend

G*E study related association result (count: 1)

Reference	Phenotype	Environment	Marker	Gene's Category
Ashley-Koch, A. E.,2015	Current PTSD	Childhood trauma	rs7866350	Non-significant

Gene functional annotation

Gene related GO terms (count: 8)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0005515	protein binding	molecular function	IPI[22354992]	169
GO:0043547	positive regulation of GTPase activity	biological process	IDA[20116244]	13
GO:0045296	cadherin binding	molecular function	IPI[20116244]	4
GO:0016023	cytoplasmic, membrane-bounded vesicle	cellular component	IEA	6
GO:0030054	cell junction	cellular component	IDA[20116244]	24
GO:0031410	cytoplasmic vesicle	cellular component	IDA[20116244]	4
GO:0005096	GTPase activator activity	molecular function	IDA[20116244]	9
GO:1902017	regulation of cilium assembly	biological process	IMP[17646400]	2

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 3)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
TBC1D2	INTS9	No	biochemical	colocalization	22863883
TBC1D2	MAP1LC3A	No	--	--	22354992 , 22354992
TBC1D2	GABARAPL1	No	--	--	22354992 , 22354992