Gene Report

Basic Info

Approved Symbol	MYLIP
Symbol Alias	"MIR\|IDOL"
Approved Name	myosin regulatory light chain interacting protein
Name Alias	E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor
Location	6p22.3
Position	chr6:16129125-16148248, 1
External Links	HGNC: 21155 Entrez Gene: 29116 Ensembl: ENSG00000007944 UCSC: uc003nbq.3
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0016874	ligase activity	molecular function	IEA	7
GO:0042632	cholesterol homeostasis	biological process	IEA	8
GO:0005515	protein binding	molecular function	IPI[12826659\|25416956]	169
GO:0045732	positive regulation of protein catabolic process	biological process	IEA	2
GO:0005856	cytoskeleton	cellular component	IEA	12
GO:0019898	extrinsic component of membrane	cellular component	IEA	3
GO:0004842	ubiquitin-protein transferase activity	molecular function	IDA[14550572]	5
GO:0008092	cytoskeletal protein binding	molecular function	IDA[10593918]	5
GO:0006928	movement of cell or subcellular component	biological process	IMP[10593918]	3
GO:0005622	intracellular	cellular component	IDA[10593918]	15
GO:0010989	negative regulation of low-density lipoprotein particle clearance	biological process	IEA	2
GO:0032803	regulation of low-density lipoprotein particle receptor catabolic process	biological process	IEA	1
GO:0007399	nervous system development	biological process	IMP[10593918]	7
GO:0005737	cytoplasm	cellular component	IEA	109
GO:0005886	plasma membrane	cellular component	IEA	99
GO:0031648	protein destabilization	biological process	IEA	2
GO:0061630	ubiquitin protein ligase activity	molecular function	IDA[21685362]	5
GO:0008270	zinc ion binding	molecular function	IEA	26
GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	biological process	IEA	2
GO:0016567	protein ubiquitination	biological process	IDA[14550572]	9

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 2)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
MYLIP	CNPY2	No	--	--	12826659 , 12826659 , 12826659 , 12826659
MYLIP	UBE2D4	No	--	--	21685362