Gene Report

Basic Info

Approved Symbol	GHRHR
Approved Name	growth hormone releasing hormone receptor
Location	7p14
Position	chr7:30938669-30993254, 1
External Links	HGNC: 4266 Entrez Gene: 2692 Ensembl: ENSG00000106128 UCSC: uc003tbx.3
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 39)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0042383	sarcolemma	cellular component	IEA	7
GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep	biological process	IEA	1
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	biological process	NAS[11773624]	1
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	biological process	IDA[1333056]	2
GO:0048609	multicellular organismal reproductive process	biological process	NAS[15944917]	2
GO:0005886	plasma membrane	cellular component	IDA[10461027]; TAS	99
GO:0071333	cellular response to glucose stimulus	biological process	IEA	4
GO:0005637	nuclear inner membrane	cellular component	IDA[10461027]	1
GO:0032869	cellular response to insulin stimulus	biological process	IEA	2
GO:0043627	response to estrogen	biological process	IDA[9482665]	5
GO:0007166	cell surface receptor signaling pathway	biological process	IEA	16
GO:0008340	determination of adult lifespan	biological process	IEA	3
GO:0032868	response to insulin	biological process	IMP[17356054]	2
GO:0007190	activation of adenylate cyclase activity	biological process	IEA	6
GO:0005737	cytoplasm	cellular component	IDA[10461027]	109
GO:0016520	growth hormone-releasing hormone receptor activity	molecular function	IMP[7680413]	1
GO:0030819	positive regulation of cAMP biosynthetic process	biological process	IDA[1333056\|7680413]	2
GO:0048469	cell maturation	biological process	IEA	1
GO:0016021	integral component of membrane	cellular component	IDA[1333056]	56
GO:0007595	lactation	biological process	IEA	3
GO:0009986	cell surface	cellular component	IDA[1333056]	21
GO:0017046	peptide hormone binding	molecular function	IPI[7680413]	3
GO:0060133	somatotropin secreting cell development	biological process	IEA	1
GO:0030141	secretory granule	cellular component	IDA[10461027]	4
GO:0030252	growth hormone secretion	biological process	IEA	2
GO:0019838	growth factor binding	molecular function	IPI[7680413]	1
GO:0051384	response to glucocorticoid	biological process	IDA[9482665]	3
GO:0030104	water homeostasis	biological process	IEA	1
GO:0042445	hormone metabolic process	biological process	IEA	2
GO:0005640	nuclear outer membrane	cellular component	IDA[10461027]	1
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	biological process	IEA	1
GO:0051246	regulation of protein metabolic process	biological process	IEA	1
GO:0060124	positive regulation of growth hormone secretion	biological process	NAS[11773624]	3
GO:0005515	protein binding	molecular function	IPI[1333056\|7680413]	169
GO:0004930	G-protein coupled receptor activity	molecular function	IC[1333056]	7
GO:0016363	nuclear matrix	cellular component	IDA[10461027]	3
GO:0019933	cAMP-mediated signaling	biological process	IMP[7680413]	4
GO:0040018	positive regulation of multicellular organism growth	biological process	IMP[8528260]	3
GO:0008284	positive regulation of cell proliferation	biological process	IDA[12867592]	14

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in PTSDgene
hsa04080	Neuroactive ligand-receptor interaction	22

Gene related interactors from protein-protein interactions data in PINA v2 (count: 1)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
GHRHR	GHRL	No	--	--	10461027