Gene Report

Basic Info

Approved Symbol	DDX39B
Previous Symbol	BAT1
Symbol Alias	"D6S81E\|UAP56"
Approved Name	DEAD-box helicase 39B
Previous Name	"HLA-B associated transcript 1\|DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B"
Name Alias	U2AF65-associated protein 56
Location	6p21.33
Position	chr6:31530219-31542448, -1
External Links	HGNC: 13917 Entrez Gene: 7919 Ensembl: ENSG00000198563 UCSC: uc003ntu.3
No. of Association Results	0. Gene is from "Mapped by LD-proxy"
Annotation Type	Mapped by LD-proxy

Gene functional annotation

Gene related GO terms (count: 32)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0016363	nuclear matrix	cellular component	IEA	3
GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development	biological process	IEA	1
GO:0008186	RNA-dependent ATPase activity	molecular function	IDA[17562711]	1
GO:0032786	positive regulation of DNA-templated transcription, elongation	biological process	IMP[22144908]	1
GO:1904707	positive regulation of vascular smooth muscle cell proliferation	biological process	IEA	1
GO:0005681	spliceosomal complex	cellular component	IDA[18593880]	1
GO:0044822	poly(A) RNA binding	molecular function	IDA[22658674\|22681889]	15
GO:0005515	protein binding	molecular function	IPI[11979277\|14667819\|15047853\|15870275\|19836239\|21859714\|23299939\|25662211]	169
GO:0017070	U6 snRNA binding	molecular function	IDA[18593880]	1
GO:0000245	spliceosomal complex assembly	biological process	IDA[18593880]	1
GO:0016607	nuclear speck	cellular component	IEA	3
GO:0005634	nucleus	cellular component	IDA[21859714]	81
GO:0043008	ATP-dependent protein binding	molecular function	IDA[18593880]	1
GO:0006974	cellular response to DNA damage stimulus	biological process	IBA	5
GO:0032403	protein complex binding	molecular function	IEA	8
GO:2000573	positive regulation of DNA biosynthetic process	biological process	IEA	2
GO:0008380	RNA splicing	biological process	IDA[18593880]	4
GO:2000002	negative regulation of DNA damage checkpoint	biological process	IMP[22144908]	1
GO:0005654	nucleoplasm	cellular component	IDA	43
GO:0001889	liver development	biological process	IEA	4
GO:0000346	transcription export complex	cellular component	IDA[15833825\|15998806]	1
GO:0005737	cytoplasm	cellular component	IDA[21859714]	109
GO:0005688	U6 snRNP	cellular component	IDA[18593880]	1
GO:0004004	ATP-dependent RNA helicase activity	molecular function	IDA[17562711\|18593880]	1
GO:0046784	viral mRNA export from host cell nucleus	biological process	IDA[18974867]	1
GO:0010501	RNA secondary structure unwinding	biological process	IDA[18593880]	1
GO:0006406	mRNA export from nucleus	biological process	IDA[17190602]; IGI[15047853]	2
GO:0005687	U4 snRNP	cellular component	IDA[18593880]	2
GO:0000398	mRNA splicing, via spliceosome	biological process	IGI[15047853]	4
GO:0030621	U4 snRNA binding	molecular function	IDA[18593880]	2
GO:0045727	positive regulation of translation	biological process	IEA	2
GO:0005524	ATP binding	molecular function	IEA	23

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 32)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
DDX39B	CHTOP	No	--	--	14667819
DDX39B	VPS33B	No	biochemical	colocalization	22939629
DDX39B	NRF1	No	--	colocalization	24250222
DDX39B	DHX38	No	biochemical	colocalization	22939629
DDX39B	BARD1	No	--	--	22990118
DDX39B	ALYREF	No	biochemical	association, colocalization	15998806 , 14667819 , 15998806 , 22939629 , 17190602 , 15047853 , 17190602 , 17190602 , 15998806 , 21799930 , 17190602 , 14667819 , 11979277 , 11979277
DDX39B	RBM39	No	--	--	14667819
DDX39B	LSM4	No	biochemical	colocalization	22939629
DDX39B	THOC2	No	biochemical	association, colocalization	11979277 , 11979277 , 15998806 , 15998806 , 17190602 , 17190602 , 17190602 , 15998806 , 17190602 , 22939629
DDX39B	SREK1	No	--	--	14559993 , 14559993
DDX39B	STRN4	No	--	--	16169070 , 16169070 , 16169070 , 16169070 , 16169070
DDX39B	THOC3	No	--	association	15998806 , 15998806 , 17190602 , 11979277
DDX39B	FYTTD1	No	--	--	19836239 , 19836239 , 19836239
DDX39B	NDRG1	Yes	biochemical	colocalization	22863883
DDX39B	ZHX1	No	--	--	14667819 , 14667819
DDX39B	THOC1	No	biochemical	association, colocalization	11979277 , 11979277 , 15998806 , 15998806 , 17190602 , 22939629
DDX39B	WDR74	Yes	biochemical	colocalization	22939629
DDX39B	THOC6	No	--	association	15998806 , 15998806 , 17190602
DDX39B	EIF4A2	No	biochemical	colocalization	22939629
DDX39B	MAGOHB	No	biochemical	colocalization	22939629
DDX39B	HIPK2	No	--	--	14667819 , 14667819
DDX39B	HNRPLL	No	--	--	14667819 , 14667819 , 14667819 , 14667819 , 14667819 , 14667819 , 14667819 , 14667819
DDX39B	RBM8A	No	biochemical	association, colocalization	23084401 , 22939629
DDX39B	C12orf10	No	biochemical	colocalization	22863883
DDX39B	THOC7	No	--	association	15998806 , 17190602 , 15998806
DDX39B	WIBG	No	biochemical	colocalization	22939629
DDX39B	DNAJC14	No	--	--	14667819 , 14667819 , 14667819 , 14667819 , 14667819 , 14667819
DDX39B	HDAC5	No	--	--	21081666
DDX39B	SUZ12	No	--	--	24457600
DDX39B	RNF2	No	--	--	24457600
DDX39B	ELAVL1	No	--	--	19322201
DDX39B	WWOX	No	--	--	24550385