Gene Report

Basic Info

Approved Symbol	BLOC1S2
Symbol Alias	"MGC10120\|FLJ30135\|BLOS2\|BORCS2"
Approved Name	biogenesis of lysosomal organelles complex 1 subunit 2
Name Alias	"centrosome protein oncogene\|Biogenesis of Lysosome-related Organelles complex-1 Subunit 2\|BLOC-1 subunit 2"
Location	10q24.31
Position	chr10:100273280-100286712, -1
External Links	HGNC: 20984 Entrez Gene: 282991 Ensembl: ENSG00000196072 UCSC: uc001kqw.2
No. of Association Results	0. Gene is from "rSNP target"
Annotation Type	rSNP target

Gene functional annotation

Gene related GO terms (count: 23)

ID	Name	Type	Evidence[PMID]	No. of Genes in PTSDgene
GO:0005515	protein binding	molecular function	IPI[15102850\|18188704\|18329849\|22203680\|23414517\|25416956]	169
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	biological process	IDA[18188704]	3
GO:0005739	mitochondrion	cellular component	IDA[18188704]	29
GO:0055037	recycling endosome	cellular component	IEA	2
GO:0016491	oxidoreductase activity	molecular function	IBA	1
GO:0031175	neuron projection development	biological process	ISS	8
GO:0055114	oxidation-reduction process	biological process	IBA	18
GO:0008284	positive regulation of cell proliferation	biological process	IDA[15381421]	14
GO:0030424	axon	cellular component	IEA; ISS	16
GO:0005634	nucleus	cellular component	IDA[18329849]; IEA	81
GO:0031083	BLOC-1 complex	cellular component	IDA[15102850\|22203680]	2
GO:0008089	anterograde axonal transport	biological process	ISS	3
GO:0048490	anterograde synaptic vesicle transport	biological process	ISS	2
GO:0008022	protein C-terminus binding	molecular function	IEA; IPI[18329849]	4
GO:0060155	platelet dense granule organization	biological process	NAS[15102850]	2
GO:0032438	melanosome organization	biological process	NAS[15102850\|22203680]	2
GO:0007020	microtubule nucleation	biological process	NAS[15381421]	1
GO:0097345	mitochondrial outer membrane permeabilization	biological process	IDA[18188704]	1
GO:0043015	gamma-tubulin binding	molecular function	IDA[15381421]	2
GO:0005813	centrosome	cellular component	IDA[15381421]; IEA	9
GO:0000930	gamma-tubulin complex	cellular component	IDA[15381421]	1
GO:0045893	positive regulation of transcription, DNA-templated	biological process	IDA[18329849]	11
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	biological process	IEA	25

Gene related KEGG pathways (count: 0)

Gene related interactors from protein-protein interactions data in PINA v2 (count: 10)

Gene	Interactor	Interactor in PTSDgene?	Experiment Method	Interaction Type	PMID
BLOC1S2	PAM16	No	--	--	21900206 , 21900206 , 21900206
BLOC1S2	OSBPL9	No	--	--	19615732 , 19615732
BLOC1S2	WASH1	No	--	--	23974797
BLOC1S2	BLOC1S4	No	biochemical	association	12191018 , 22203680 , 22203680 , 22203680 , 15102850 , 15102850 , 15102850 , 15102850 , 15102850
BLOC1S2	C8orf33	No	--	--	21900206 , 21900206 , 21900206
BLOC1S2	BLOC1S6	No	biochemical	association	15102850 , 15102850 , 15102850 , 15102850 , 15102850 , 15102850 , 12191018 , 15102850 , 22203680 , 22203680 , 22203680
BLOC1S2	IFT57	No	--	--	18188704 , 18188704 , 18188704
BLOC1S2	RDH11	No	--	--	21900206 , 21900206 , 21900206
BLOC1S2	BLOC1S5	No	biochemical	association	15102850 , 15102850 , 15102850 , 15102850 , 15102850 , 12191018 , 15102850 , 22203680 , 22203680 , 22203680
BLOC1S2	DTNBP1	Yes	biochemical	association	15102850 , 15102850 , 15102850 , 12191018 , 15102850 , 22203680 , 22203680 , 22203680 , 22203680 , 22203680 , 22203680