PTSDgene database

Study Report

Study Information
Basic Info
Reference
Citation Lee, H. J., et al. (2005). "Influence of the serotonin transporter promoter gene polymorphism on susceptibility to posttraumatic stress disorder." Depress Anxiety 21(3): 135-139.
Phenotype PTSD diagnosis
Trauma Various
Study Design Case-control
Study Type Candidate gene association study
Sample Size 100 cases, 197 controls
SNP/Marker Size 1 Variant
Predominant Ethnicity Mongloid
Population Korean
Gender Case: 57 females, 43 males. Control: 121 females, 76 males
Age Case: mean age=35.29 years, SD=10.29; control: mean age=34.76 years, SD=11.06

Detail Info

Genetic result reported by this study
Normal genetic result reported by this study (count: 1)
Marker Phenotype Related Gene Statistical Values Author Comments Marker's Category
SERTPR PTSD diagnosis SLC6A4 Genotypes: X2=4.18, P-value=0.124; allele: X2=4.05, P-value=0.044, OR=1.65, 95%CI: 1.01-2.68. When the genotypes of SERTPR were dichotomized into s/s and l/s+l/l groups, X2=4.14, P-value=0.042, OR=1.77, 95%CI: 1.02-3.06. There were marginal differences in genotypes between the two...... There were marginal differences in genotypes between the two groups, and the allele frequency was significantly different, when the genotype of SERTPR were dichotomized into s/s and l/s+l/l groups, the frequency of the s/s genotype was significantly higher in patients with PTSD. More... Significant