SNP Report

Basic Info

Name	rs9306235 dbSNP Ensembl
Location	22:19967634 - 19967634(+)
Variant Seq	A,T
Ancestral Allele	G
Ref Seq	G
Minor Allele Frequence	0.028155
Annotation	downstream_gene_variant; 3_prime_UTR_variant; intron_variant; NMD_transcript_variant
Variant Effect	downstream_gene_variant(ENST00000406522, ENST00000495096, ENST00000493893, ENST00000403184, ENST00000467943, ENST00000406259, ENST00000585066, ENST00000401994, ENST00000263207); 3_prime_UTR_variant(ENST00000428707); intron_variant(ENST00000449653, ENST00000207636, ENST00000412786, ENST00000407537, ENST00000406520, ENST00000361682, ENST00000403710); NMD_transcript_variant(ENST00000207636)
SIFT Annotation	tolerated
SIFT Variant Effect	tolerated(ENST00000401994, ENST00000406259, ENST00000406522, ENST00000263207)
PolyPhen Annotation	benign
PolyPhen Variant Effect	benign(ENST00000401994, ENST00000406259, ENST00000406522, ENST00000263207)
rSNP?	No Link in rVarBase
Related Regulatory Elements	N.A.
Chromatin State	N.A.
No. of Marker's Association Results	1 (Positive: 0; Negative: 1; Trend: 0)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Wolf, E. J.,2014	Dissociative symptom severity	Association with dissociation: P-value= .04, gene-wide perm...... Association with dissociation: P-value= .04, gene-wide permutation testing: P-value= .42. More...	It showed a nominally significant association that did not w...... It showed a nominally significant association that did not withstand gene-wide permutation testing. More...	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	22q11.21	Mapped by Literature SNP, Mapped by LD-proxy
COMT	catechol-O-methyltransferase	22q11.21	21(9/12/0)

SNPs in LD with rs9306235 (count: 1)

The LD data used here is based on 1000 Genome Phase I. LD SNP pairs were selected with a threshold r²<=0.8.

rs_ID	Literature-origin SNPs with LD	Annotation	r²[population]
rs11089325	rs9306235	intron_variant; non_coding_transcript_variant	0.8584[EUR]

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
FBLL1	No	Adipose Subcutaneous	cis	GTEx