PTSDgene database

Pathway Enrichment Analysis Protein-Protein Interaction Analysis

SNP Report

Basic Info

Name	rs71355256 dbSNP Ensembl
Location	17:409457 - 409457(+)
Variant Seq	T
Ancestral Allele	C
Ref Seq	C
Minor Allele Frequence	0.0549121
Annotation	non_coding_transcript_exon_variant; upstream_gene_variant; intron_variant; non_coding_transcript_variant
Variant Effect	non_coding_transcript_exon_variant(ENST00000599026); upstream_gene_variant(ENST00000575151, ENST00000491373, ENST00000360127, ENST00000629953, ENST00000571106); intron_variant(ENST00000466740, ENST00000629249); non_coding_transcript_variant(ENST00000466740, ENST00000599026, ENST00000629249)
SIFT Annotation	deleterious
SIFT Variant Effect	deleterious(ENST00000575130, ENST00000573448, ENST00000574722, ENST00000575634, ENST00000618002, ENST00000573780, ENST00000570638, ENST00000577079, ENST00000331302, ENST00000575736, ENST00000573588, ENST00000323434, ENST00000576420, ENST00000536489)
PolyPhen Annotation	probably_damaging
PolyPhen Variant Effect	probably_damaging(ENST00000575130, ENST00000573448, ENST00000574722, ENST00000575634, ENST00000618002, ENST00000573780, ENST00000570638, ENST00000577079, ENST00000331302, ENST00000575736, ENST00000573588, ENST00000323434, ENST00000576420, ENST00000536489)
rSNP?	Yes Link in rVarBase
Related Regulatory Elements	TF binding region;Chromatin interactive region;lncRNA
Chromatin State	Enhancers;Weak transcription;Active TSS;Flanking Active TSS;Genic enhancers;Transcr. at gene 5' nd 3';Bivalent Enhancer
No. of Marker's Association Results	1 (Positive: 0; Negative: 0; Trend: 1)
Source	Literature

SNP related association results

Normal genetic study related association results (count: 1)

Reference	Phenotype	Statistical Values	Author Comments	Marker's Category
Logue, M. W.,2013	PTSD	In discovery group (allele): OR=3.7, P-value=4.3E-06. In discovery group (allele): OR=3.7, P-value=4.3E-06.	It reached the suggestive level of significance in discovery...... It reached the suggestive level of significance in discovery group. More...	Trend

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Association Results (Positive/Negative/Trend)
RPH3AL	rabphilin 3A-like (without C2 domains)	17p13.3	rSNP target
C17orf97	chromosome 17 open reading frame 97	17p13.3	1(0/0/1)

SNPs in LD with rs71355256 (count: 0)

SNP related eQTL (count: 1)

Gene Symbol	Gene Existed in PTSDgene?	Tissue	Trans/Cis	Source
DND1P1	No	Adipose Subcutaneous	cis	GTEx